Antimicrobial Resistance & Infection Prevention Epi-Center (C-PIE)


Dr. William Trick is Principal Investigator of the CDC-funded Chicago Prevention and Intervention Epi-center program. CDC began the Prevention Epi-Center Program as a way to work directly with academic partners to address important scientific questions regarding the prevention of healthcare-associated infections, antibiotic resistance, and other adverse events associated with healthcare.

Recent and ongoing Prevention Epicenter research studies and demonstration projects include:

• Collaboration among centers to implement and evaluate strategies to reduce transmission of antimicrobial resistant organisms among patients in intensive care units using novel approaches to routine skin antisepsis.
• A multi-center study of a novel approach to using administrative and pharmacy data to make surveillance for surgical site infections (SSIs) simpler and more accurate. The novel approach can decrease the labor required for the surveillance and yet substantially increase sensitivity of detection.
• A multi-center study to determine baseline incidence of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcus (VRE) transmission in 12 intensive care units (ICUs) in five hospitals. The study demonstrated that active surveillance cultures increase detection of MRSA and VRE colonization in ICUs by up to 49%.